Recently, the research and development of new coronavirus vaccines in various countries in the world has entered the sprint stage. my country currently has 5 new coronavirus vaccines undergoing phase III clinical trials in preparation for large-scale production. Two companies, Pfizer and Modena, have announced that their new coronavirus vaccine phase III clinical trials have achieved positive results, but they must be stored at -70°C to maintain their effectiveness. Before a large number of vaccines poured into the market, the transportation and storage of vaccines became an urgent problem to be solved, and ultra-low temperature refrigerators can be said to be a feasible solution to this problem.

According to the experimental data released by some foreign pharmaceutical companies, the storage conditions of the new crown vaccine are strict and must be stored under low temperature conditions. It can maintain activity at temperatures below -20°C or even -86°C.

“Compared with dry ice, using professional ultra-low temperature equipment, the ambient temperature is more uniform, there will be no local temperature differences, which will affect the effectiveness of the vaccine.”

Ultra-low temperature refrigerator is the general name of refrigerator products used in medical and health, biological sample storage, new drug research and development, and low-temperature experiments of special materials. It is a key equipment for the preservation of biological materials such as medicines, genes, cells, etc.

“The advent of the new coronavirus vaccine will undoubtedly bring more market space for medical ultra-low temperature refrigerators, and it is an opportunity for Chinese home appliance companies. First, the domestic production environment and order are stable. Since the outbreak, compared with overseas markets, Insufficient production capacity, the global home appliance production capacity has significantly increased dependence on China, and domestic refrigerator product exports have shown explosive growth. Secondly, the demand for ultra-low temperature refrigerators has grown steadily, and domestic technical strength can be covered. During the Ebola virus raging period, Aucma and other companies The medical ultra-low temperature refrigerator products show excellent technical strength, and can still achieve ultra-low temperature freezing for a long time under the environment of lack of electricity and high temperature. Finally, the brand influence goes abroad. In recent years, Chinese home appliance companies have accounted for the global market The ratio has gradually increased, and the recognition of Chinese home appliance brands in the international market has increased significantly.

For a long time, the ultra-low temperature refrigeration equipment market in China’s medical field has been monopolized by foreign brands, and the products are expensive, which has burdened medical institutions, pharmaceutical companies, scientific research departments, and users with a heavy economic burden. For the industry, domestic home appliance companies continue to break through the technical barriers of ultra-low temperature refrigerators. Through independent innovation, they not only fill the gap in demand, but also become a powerful promoter of the progress and industrial development of China’s low-temperature refrigeration industry.

For enterprises, through medical cold chain and biomedicine, they can enter the broader fields of medical and life sciences, break the long-term monopoly of foreign brands on the cutting-edge Chinese cryogenic cold chain market, and become a promoter of the progress and industrial development of China’s cryogenic refrigeration industry It also provides greater possibilities for the development of enterprises in the biomedical field.

Products can meet all levels of ultra-low temperature requirements

After acute infectious atypical pneumonia, the research and development of epidemic infectious disease vaccines has attracted much attention, and the ultra-low temperature refrigerator market has also flourished. For now, breakthroughs have been made in the technology of medical ultra-low temperature refrigerators, but there are certain technical barriers.

Ultra-low temperature accessibility, long-term stability and uniformity have become the technical key points of ultra-low temperature refrigerators. First of all, ultra-low temperature and deep cryogenic technologies such as -196℃, -150℃, -86℃ are far less than ordinary refrigeration technology reaching more than ten degrees below zero, and a new set of refrigeration system needs to be developed; secondly, biomedical cryogenic storage is emphasized Long-term storage, stable and reliable, and there should be no unacceptable conditions such as the sudden failure of the equipment during use and the damage of precious samples. The long-term stability of storage is a crucial point in the core technology. Finally, a certain storage device in the biological sample library must To store up to 60,000 samples, the temperature of each point in the space is required to be the same, and the temperature in the center area and the surrounding area cannot be different.

On the basis of technological breakthroughs, the ecology of ultra-low temperature refrigerator products of Chinese home appliance companies has gradually enriched

Ultra-low temperature refrigerator capacity to be tested

Judging from the current global situation, cryopreservation and transportation are no small challenges for the distribution of new crown vaccines. It is understood that the United States began to distribute vaccines in mid-December, resulting in almost sold out of inventories of ultra-low temperature refrigerator manufacturers across the United States. Dan Hensler, vice president of Solo Environmental Equipment Company, said that since the spring of this year, the stockpiled inventory has been exhausted in three weeks, and the next order delivery will take about six to eight weeks. Globally, there is a strong demand for ultra-low temperature freezers.In addition, ultra-low temperature refrigerator manufacturers need to work closely with vaccine manufacturers and pharmaceutical companies to help medical institutions manage the inventory of vaccines and reagents through IoT solutions and help pharmaceutical commercial companies understand market demand. This is a win-win model that needs to be explored in the future.

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